In androgen-responsive target tissues such as the skin, scalp, and prostate, the high relative androgenicity of testosterone is dependant on its reduction to dihydrotestosterone (DHT). The 5-alpha reductase enzyme is responsible for this metabolism of testosterone. The concurrent use of a 5-alpha reductase inhibitor such as finasteride or dutasteride will interfere with site-specific potentiation of testosterone action, lowering the tendency of testosterone drugs to produce androgenic side effects. It is important to remember that both anabolic and androgenic effects are mediated via the cytosolic androgen receptor. Complete separation of testosterone’s anabolic and androgenic properties is not possible, even with total 5-alpha reductase inhibition.
Because the ultimate goal of a steroid cycle is to increase strength and muscle size, the associated spike in estrogen which accompanies steroids such as Testosterone is considered undesirable. In order to disassociate the two effects, two classes of drug are used. Medications such as Nolvadex or Clomid target the estrogen receptors. They make it more difficult for the estrogen to exert it’s influence within the body thus allowing the testosterone to act more freely. The second class is aromatase inhibitors such as Femara. They target the aromatase enzyme itself in order to prevent the production of estrogen in the first place. Sometimes, it’s not always clear which option you should go with or even what the differences are between the two. Lets clear that up a little.
As the only steroid in the course, but the best effect is achieved when combined with other drugs. Start using anabolic agents athletes may recommend a dose of 50 mg of propionate every two days. The usual dose of the most experienced athletes propionate 100 mg a day or more.
Be sure to take anti-estrogen drugs, such Proviron or aromatase inhibitors as usual, from the second week to prevent the development of gynecomastia, water retention, and other effects of estrogen. After the introduction of post-therapy cycle is carried out, is the most commonly used tamoxifen. Furthermore, it is desired that the output of cortisol blockers to preserve reception weight gain. Be sure to follow the diet for a set of weights, and take sports nutrition.