Propionate volatile fatty acid

The short-chain fatty acid butyrate is particularly important for colon health because it is the primary energy source for colonic cells and has anti- carcinogenic as well as anti-inflammatory properties [7] that are important for keeping colon cells healthy. [8] [9] Butyrate inhibits the growth and proliferation of tumor cell lines in vitro, induces differentiation of tumor cells, producing a phenotype similar to that of the normal mature cell, [10] and induces apoptosis or programmed cell death of human colorectal cancer cells. [11] [12] Butyrate inhibits angiogenesis by inactivating Sp1 transcription factor activity and downregulating VEGF gene expression. [13]

Propionate volatile fatty acid

propionate volatile fatty acid

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